NANOSIZED CUBOSOMAL THERMOGELLING DISPERSION LOADED WITH SAQUINAVIR MESYLATE TO IMPROVE ITS BIOAVAILABILITY: PREPARATION, OPTIMIZATION, IN VITRO AND IN VIVO EVALUATION

Khaled M Hosny1,2 1Department of Pharmaceutics, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Saudi Arabia; 2Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, EgyptCorrespondence: Khaled M HosnyDepartment of Pharmaceutics, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Saud

Many factors (internal and Wooden Key Holder external) can make a business vulnerable.In the context of the international financial crisis, the firms, and especially the small and mediume enterprises (SMEs) have to face new challenges.Smaller businesses are particularly prone to financial difficulties as they often lack resources to adapt to the ch

In the era of big data, one of the key challenges is to discover process models and gain insights into business processes by analyzing event data recorded in information systems.However, Chaotic activity or infrequent behaviors often appear in actual event logs.Process models containing such behaviors are complex, difficult to understand, and hide

Abstract Density-wave fronts in a vibrofluidized wet granular layer undergoing a gas-liquid-like transition are investigated experimentally.The threshold of the instability is governed by the GUTSHOT GARLIC DILL PICKLE amplitude of the vertical vibrations.Fronts, which are curved into a spiral shape, propagate coherently along the circular rim of t